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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 433-440Analysis of 2,6-Dinitrotoluene Toxicity to Common...

Analysis of 2,6-Dinitrotoluene Toxicity to Common Carp (Cyprinus carpio)

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Abstract:

2,6-dinitrotoluene (2,6-DNT) is the preferential toxicants stipulated by OECD and EPA of USA. The present study was conducted to determine the effect of 2,6-DNT chemical on acute toxicity and subacute toxicity in common carp (Cyprinus carpio). The 24h, 48h, 72h and 96h LC50 values of common carp by 2,6-DNT were 1.137±0.023mg/L, 0.830±0.024mg/L, 0.661±0.019mg/L and 0.479±0.020mg/L, respectively. The subacute experiment shows that C. carpio are rarely affected by 0.0251mg/L 2,6-DNT, but significantly affected by 0.0398, 0.0631, 0.0794mg/L 2,6-DNT in contrast to the controlled sample (p liver > kidney.

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Materials Science and Information Technology

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Periodical:

Advanced Materials Research (Volumes 433-440)

Pages:

798-804

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.433-440.798

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Online since:

January 2012

Authors:

Ai Rong Zheng, Jing Bo Xu

Keywords:

2‚6-Dinitrotoluene (2‚6-DNT), Common Carp (Cyprinus carpio), Na+/K+-ATPase Activity, Toxicity

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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[8] 10±0. 45.

[24] 0±4. 0 24.

[1] 137±0. 023.

[2] 688 (2. 476~2. 900) 48.

830±0. 024.

[2] 064 (1. 850~2. 278) 72.

661±0. 019.

[1] 484 (0. 912~2. 056) 96.

479±0. 020.

[1] 352 (1. 180~1. 524) 112.

[1] 341 (1. 120~1. 562) TABLE II. Effect of 2, 6-DNT on C. carpio growth (average length mm, n = 15) concentration (mg/L) 0d 10d (% increase length) 20d (% increase length) 30d (% increase length) control.

[7] 92±0. 44.

[9] 04±0. 40 (14. 1).

[10] 37±0. 47 (14. 7).

[11] 49±0. 49 (10. 8) solvent control (<0. 0001).

[7] 96±0. 36.

[9] 11±0. 37 (14. 4).

[10] 39±0. 49 (14. 1).

[11] 51±0. 47 (10. 8).

0251.

[7] 99±0. 34.

[9] 20±0. 39 (15. 1).

[10] 14±0. 50 (10. 2).

[11] 03±0. 50 (8. 78).

0398.

[7] 94±0. 40.

[9] 05±0. 42 (14. 0).

[9] 89±0. 57 (9. 28) *10. 68±0. 55 (7. 99).

0631.

[8] 00±0. 39.

[8] 65±0. 50 (8. 12) *9. 33±0. 46 (7. 86) *10. 10±0. 46 (8. 25).

0794.

[7] 98±0. 31.

[8] 51±0. 44 (6. 64) *9. 22±0. 45 (8. 34) *9. 64±0. 48 (4. 56) TABLE III. The results of accumulative toxicity test of 2, 6-DNT for C. carpio time (d) 9 11 14 16 19 21 23 concentration (mg/L).

310.

310.

464.

464.

710.

[1] 065.

[1] 065 accumulative dose (mg/L).

427.

590.

894.

[1] 137.

[1] 688.

[2] 125.

[2] 657 ln of Accumulative dose (mg/L) -0. 851 -0. 528 -0. 112.

128.

524.

754.

977 death probit.

[3] 72.

[4] 16.

[4] 48.

[4] 75.

[5] 00.

[5] 25.

[5] 39 dead rate (%) 10 20 30 40 50 60 65 TABLE IV. Na+/K+-ATPase activity in gill, kidney and liver for C. carpio exposed to 2, 6-DNT concentration Na+/K+-ATPase activity (nmol pi/mg/h, mean±s) gill percentage (%) inhibitation percentage (%) kidney percentage (%) inhibitation percentage (%) liver percentage (%) inhibitation percentage (%) control.

DOI: 10.1787/451478345276

[26] 80±1. 22.

[45] 27±1. 31.

[79] 34± 1. 23 solvent control.

[26] 96±1. 33.

[45] 21±1. 29.

[79] 31± 1. 25.

024.

[26] 23±1. 29.

[87] 9.

[12] 1.

[41] 79±1. 35.

[92] 3.

[7] 7.

[73] 51± 1. 24.

[92] 7.

[7] 3.

042.

[24] 15±1. 23.

[80] 1.

[19] 9.

[37] 23±1. 22.

[82] 2.

[17] 8.

[67] 51± 1. 35.

[85] 1.

[14] 9.

075.

[20] 77±1. 11.

[67] 5.

[32] 5.

[33] 69±1. 51.

[74] 4.

[25] 6.

[60] 31± 1. 45.

[76] 0.

[24] 0.

100.

[18] 16±1. 10.

[57] 8.

[42] 2.

[30] 05±1. 30.

[66] 4.

[33] 6.

[56] 17± 1. 39.

[70] 8.

[29] 2.

135.

[14] 27±1. 77.

[43] 2.

[56] 8.

[25] 83±1. 13.

[57] 1.

[42] 9.

[45] 39± 1. 31.

[57] 0.

[43] 0.

240.

[12] 48±1. 98.

[36] 6.

[63] 4.

[22] 19±1. 09.

[49] 0.

[50] 9.

[34] 29± 1. 27.

[43] 2.

[56] 8.

420.

[7] 09± 0. 76.

[16] 5.

[83] 5.

[14] 00±0. 91.

[30] 9.

[69] 1.

[21] 14± 1. 23.

[26] 6.

[73] 4.