Cytochrome P4501A (CYP1A) Expression in the Liver of Feral Common Carp (Cyprinus carpio) Inhabiting a Nitrotoluene Contaminated Site

Abstract:

As a result, CYP1A expression in fishes is frequently used as a biomarker of exposure to aromatic hydrocarbon contaminants and early biological effect. We determined EROD activity and cytochrome P4501A protein level in liver of feral fish, common carp, Cyprinus carpio inhabiting a nitrotoluene contaminated environment in this study. The results show that feral C. carpio caught from contaminated water(nitrotoluene)in Songhua River displayed induction of CYP1A at two levels of expression, namely, apoprotein level and catalytic activity in liver.

• Periodical: Advanced Materials Research (Volumes 433-440)
• Pages: 805-810
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.433-440.805
• Online since: January 2012
• Authors: Jing Bo Xu, Nan Jing
• Keywords: Cytochrome P4501A Protein, EROD, Feral Common Carp (Cyprinus carpio), Induction Expression, Nitrotoluene Contaminated Environment

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