Near-IR Sensitive Au-Au2S Nanoparticles with Biocompatibility for Drug Delivery

Wen Liu; Zu Yong Wang; Pei Yin; Lei Ren; Qi Qing Zhang

doi:10.4028/www.scientific.net/AMR.47-50.1315

Paper Titles

Irradiation of Synthesized Magnetic Nanoparticles and its Application for Hyperthermia
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Surface Morphological Changes Accompanying Dissolution of Bioactive Glass: Effect of Residual Stress
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Effect of pH Value on Synthesis of Calcium Phosphates
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Surfaces Modified by Amphiphilic Copolymer: Preparation and Application
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Near-IR Sensitive Au-Au₂S Nanoparticles with Biocompatibility for Drug Delivery
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Novel Organic-Inorganic Hybrid Nanoparticles as Non-Viral Gene Vector
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Bioassay Based on Photonic Crystal
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Distinctive Degradation Behaviors of Electrospun PGA, PLGA and P(LLA-CL) Nanofibers Cultured with/without Cell Culture
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A Retrievable Polymer Urethral Stent for Treatment of Urethral Strictures
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 47-50Near-IR Sensitive Au-Au2S Nanoparticles with...

Near-IR Sensitive Au-Au₂S Nanoparticles with Biocompatibility for Drug Delivery

Abstract:

The near-infrared (NIR) sensitive Au-Au2S nanoparticles (NPs) have shown many advantages as potential drug delivery systems. To further investigate biological safety of Au-Au2S NPs, cytotoxicity was estimated by calcein AM/EthD-1 fluorescence staining and the lactate dehydrogenase (LDH) release. The effects of NPs on apoptosis of CHL cells were determined by flow cytometry with Annexin V-FITC/PI double staining. It is evident that the Au-Au2S NPs are non-cytotoxic below IC50 dosage.