Effects of Potential Enviromental Pollutant Acaricide Fenpyroximate on Juvenile Turbot (Scophthalmus Maximus)

Abstract:

Juvenile turbot (Scophthalmus maximus) were exposed to acaricide fenpyroximate, and the subsequent histological, enzyme activity changes of liver tissue were examined. Histopathological examinations showed that the turbot liver is the target organ for the acaricide fenpyroximate. Analysis of liver antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX), in the exposed turbots also showed similar changes. These changes indicated that fenpyroximate caused the oxidative stress on the turbot liver, which induced the damage of antioxidant enzymes system and possible interruption of the mitochondrial redox respiratory chain. This could be one toxic mechanism of fenpyroximate to the juvenile turbot.

• Periodical: Advanced Materials Research (Volumes 634-638)
• Pages: 1319-1322
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.634-638.1319
• Online since: January 2013
• Authors: Pei Long Xu, Na Na, Lei Shang
• Keywords: Fenpyroximate, Liver, Pesticides, Pollutant, Toxicity, Turbot

References

[1] Motoba, K., Nishizawa, H., Suzuki, T., Hamaguchi, H., Uchida, M., Funayama, S., 2000. Species-Specific Detoxification Metabolism of Fenpyroximate, a Potent Acaricide. Pestic. Biochem. Physiol. 67, 73–84.

DOI: 10.1006/pest.2000.2477

[2] Pesticides Residue Evaluation for Fenpyroximate. Pesticides evaluated by JMPR and JMPS. Joint FAO/WHO Meeting on Pesticide Residues (JMPR), 1995. http://www.fao.org/ag/AGP/AGPP/Pesticid/JMPR/Download/95_eva/fenpyro.pdf

DOI: 10.1142/9781786341693_0004

[3] Na Na, Guo H. R., Zhang S. C., Li Z. J., Yin L. C. In vitro and in vivo acute toxicity of fenpyroximate to flounder Paralichthys olivaceus and its gill cell line FG. Aquatic Toxicology 92 (2009) 76–85.

DOI: 10.1016/j.aquatox.2008.12.006

[4] Mark, G. J. H, Michael K., David S., Carmel M., John O'Halloran, Nora M. O'Brien, and Frank N.A.M. van Pelt, 2007. Hepatic biomarkers of sediment-associated pollution in juvenile turbot, Scophthalmus maximus L. Mar. Environ. Res. 64(2), 191-208.

DOI: 10.1016/j.marenvres.2007.01.002

[5] Telli-Karakoç, F., Ruddockc, P. J., Birdc, D. J., Hewerd, A., Van Schankee, A., Phillips, D. H., and Peters, L. D., 2002. Correlative changes in metabolism and DNA damage in turbot (Scophthalmus maximus) exposed to benzo[a]pyrene. Mar. Environ. Res. 54(3-5), 511-515.

DOI: 10.1016/s0141-1136(02)00192-7

[6] Susan, M. S., Susan, C. F., Ronald, M. S., and Anne, B. J., 2000. Sub-Lethal Effects of Exposure of Juvenile Turbot to Oil Produced Water. Mar. Pollut. Bul. 40(11), 928-937.

DOI: 10.1016/s0025-326x(00)00031-x

[7] Rosety-Rodríguez, M., Ordoñez, F.J., Roldan, S., Rosety, J.M., Rosety, M., Ribelles, A., Carrasco, C., Rosety, I., 2010. Acute effects of sodium dodecyl sulphate on the survival and on morpho-histochemical characteristics of the trunk kidney of juvenile turbot Scophthalmus maximus L. Eur. J. Histochem. 46(2), 179-184.

DOI: 10.4081/1668

[8] Bradford, M. M., 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.

DOI: 10.1016/0003-2697(76)90527-3

[9] Zheng, Y., Zhang, J., Lou, Y., 2002. Influences of rat liver microsome simple preparation methods to glutathione S-tranferase activity. J. Zhejiang UNi. (Medical Sciences). 31(6), 429-432.

[10] Lemaire, P., Mathieu, A., Giudicelli, J., Lafaurie, M., 1992. Effects of diet on the responses of hepatic biotransformation enzymes to benzo(a)pyrene in the European sea bass (Dicentrarchus labrax). Comp. Biochem. Physiol. 102C, 413-420.

DOI: 10.1016/0742-8413(92)90135-t

[11] Goksøy, A., Förlin, L., 1992. The cytochrome P-450 system in fish, aquatic toxicology and environmental monitoring. Aquat. Toxico1. 22, 287-312.

DOI: 10.1016/0166-445x(92)90046-p

[12] George, S.G., 1994. Enzymology and molecular biology of Phase II xenobiotic conjugating enzymes in fish. In: Malins, D.C. Ostrander, G.K. (Eds.), Aquatic Toxicology, Molecular, Biochemical and Cellular Perspectives. Lewis, Boca Raton, FL, pp.37-85.

[13] Peters, L.D., Morse, H.R., Waters, R., Livingstone, D.R., 1997. Responses of hepatic cytochrome P4501A and formation of DNA—adducts in juveniles of turbot (Scophthalmus maximus L.) exposed to water-borne benzo[a]pyrene. Aquat. Toxicol. 38, 67-82.

DOI: 10.1016/s0166-445x(96)00838-7