The Role of 1H-MRS in Diagnosis of Elderly Chronic Alcoholic Toxic Encephalopathy

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Abstract:

Objective: This study was undertaken to study the effect of MR imaging on patients with elderly chronic alcoholic toxic encephalopathy. Methods: 20 patients with chronic alcoholic toxic encephalopathy (CATE) and 18 patients cerebral infarction diagnosed were collected to analyze conventional imaging material and spectral spectrum line shape variation peak by magnetic resonance imaging (MRI). Results: Cerebral and cerebellar vermis atrophy and abnormal signal in the deep part of the cerebral hemispheres, basal ganglia, pons asymmetric small pieces long T1 and long T2 were detected in CATE patients. And 1H-MRS also showed that the concentrations of NAA and Cho in cerebellar vermis were significantly reduced. In cerebral infarction patients declined NAA and elevated Lac were found. Conclusion: Our study suggests that 1H-MRS play a positive role in CATE diagnosis, which keeps from further damage to the brain tissue.

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Advanced Materials Research (Volumes 641-642)

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838-840

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January 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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[1] Deli Zhang. The relate diseases about alcoholism. Zhong Guo Cheng Xiang Qi Ye Wei Sheng. 2008, 124 (4): 56-57.

Google Scholar

[2] Harper C. The Neurotoxicity of Alcohol. Human & Experimental Toxicology, 2007, 26(3): 251-257.

Google Scholar

[3] Guangyi Wang, Changhong Liang, Biao Huang, et al. Magnetic resonance imaging findings in Chronic Alcoholic Toxic Encephalopathy. Radiologic Practice. 2009, 24(4): 372-375.

Google Scholar

[4] Shiping Xie, Jianxiong Fan, Lijun Chen, et al. The role of structural magnetic resonance imaging and 1H magnetic resonance spectroscopy in alcoholic cognitive impairment study. Journal of International Psychiatry. 2007, 34(4): 228-231.

Google Scholar

[5] Yufei Yao, Youqi Gao, et al. Advances of magnetic resonance spectroscopy on cerebral infarction research.  Chinese Journal of Cerebrovascular Diseases. 2010, 4(4): 293-299.

Google Scholar