Nafion/Quercetin/Graphene Composite-Modified Glassy Electrode for Selective and Sensitive Detection of Dopamine

Abstract:

Glassy carbon electrode (GCE) was modified using graphene (G), quercetin (Qu) and Nafion in this sequence to fabricate Nafion-Qu-G composite-modified GCE (Nafion/Qu/G/GCE). The as-prepared modified electrode combining the advantages of Nafion, Qu and G was employed for the selective and sensitive detection of dopamine (DA) in the presence of ascorbic acid (AA) and uric acid (UA). Compared with GCE, Qu/GCE, G/GCE and Qu/G/GCE, the Nafion/Qu/G/GCE was more electroactive and selective for DA. Differential pulse voltammetry (DPV) was used for electrochemical detection, the separations of the oxidation peak potentials for AA-DA and DA-UA were about 304 mV and 136 mV, which allowed selectively determining DA. In phosphate buffer solution (PBS) of pH 6.8, the Nafion/Qu/G/GCE provided a detection limit of 2.31×10^-8 mol/L (S/N=3) for DA. Linearity (R=0.9963) of the peak currents against the concentration of DA was found over the range of 1.0×10^-7 to 1.0×10^-3 mol/L. Furthermore, the modified electrode exhibited good reproducibility and stability.

• Periodical: Advanced Materials Research (Volumes 641-642)
• Pages: 841-844
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.641-642.841
• Online since: January 2013
• Authors: Dai Min Song, Jian Fei Xia, Zong Hua Wang, Yan Zhi Xia, Fei Fei Zhang, Lin Hua Xia
• Keywords: Differential Pulse Voltammetry, Dopamine, Graphen, Nafion, Quercetin

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