Bioinformatic Analysis and Characteristics of Glycoprotein L(gL) Encoded by UL1 Gene of Duck Plague Virus

Abstract:

Glycoprotein L(gL) is encoded by UL1 gene of duck plague virus (DPV). Through predicting and analyzing the structure and physicochemical properties of DPV gL protein by using some software and online tools to gain more information of DPV gL protein. The phylogenetic tree shows that DPV gL protein has close evolutionary relationship with the genus Simplexvirus. The online analysis of the physicochemical properties demonstrates that the protein has ten potential phosphorylation sites and five potential O-linked glycosylation sites, and without both the signal peptide and the transmembrance region. In addition, the subcellular localization of gL protein largely locates at mitochondrial with 47.8%. The secondary structure results reveal that random coil dominate among secondary structure elements followed by alpha helix, extended strand and β-turn for all sequences. All the data will help a basis for further functional and physiological features study of the DPV gL protein.

• Periodical: Advanced Materials Research (Volume 647)
• Pages: 250-257
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.647.250
• Online since: January 2013
• Authors: Ling Jie Zuo, An Chun Cheng, Ming Shu Wang
• Keywords: Bioinformatic Analysis, DPV, Envelope Glycoprotein, Glycoprotein L, UL1 Gene

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