Multi-Functional Biomemory Device Composed of Recombinant Metalloprotein

Jeong Woo Choi

doi:10.4028/www.scientific.net/AMR.647.583

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Sequence Analysis of the Cas2 Gene in Riemerella anatipestifer
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Development and Evaluation of a Loop-Mediated Isothermal Amplification (LAMP) Method for Detecting Foodborn Salmonella in Raw Milk
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Multi-Functional Biomemory Device Composed of Recombinant Metalloprotein
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Isolation and Mutagenesis of a Novel Phenol-Degrading Strain
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Optimal Control of a Tuberculosis Model with Chemoprophylaxis Treatment
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Prediction of Apoptosis Proteins Subcellular Location Using Evolutionary Profiles and Motifs Information
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Functional Characters of Corn Steeping Water Protein Concentrate
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 647Multi-Functional Biomemory Device Composed of...

Multi-Functional Biomemory Device Composed of Recombinant Metalloprotein

Abstract:

We developed a multi-functional biomemory device composed of cytochrome c and recombinant azurins which have different metal ions in the core. Azurin, one of the well-known metalloproteins, was modified by attaching cysteine residue containing thiol functional group for direct immobilization without chemical linkers. The immobilization of metalloproteins was confirmed by atomic force microscopy (AFM) and surface plasmon resonance (SPR) spectroscopy. The redox properties of immobilized recombinant azurin were validated with cyclic voltammetry (CV), and memory functions using various metalloprotein structures were confirmed by the technique of open circuit potential amperometry (OCPA). We achieved various practical functions based on basic memory functions including write, erase, and read using recombinant azurin and other metalloproteins, and this proposed multifunctional biodevice could be directly applied to the realization of bioelectronics device for next generation, such as single molecular functional device, bioprocessor and biocomputing system.

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Periodical:

Advanced Materials Research (Volume 647)

Pages:

583-587

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.647.583

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Online since:

January 2013

Authors:

Jeong Woo Choi

Keywords:

Bioelectronic Device, Biomemory, Nanobiochip, Recombinant Protein

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