Fast Detection of Local Anesthetic Ropivacaine by Impedance Method on Polypyrrole-Graphene Oxide

Ren Jang Wu; Mei Yun Chen

doi:10.4028/www.scientific.net/AMR.650.49

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Production of Highly Efficient Photocatalytic TiO₂Powders by Mechanical Ball Milling
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Fast Detection of Local Anesthetic Ropivacaine by Impedance Method on Polypyrrole-Graphene Oxide
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 650Fast Detection of Local Anesthetic Ropivacaine by...

Fast Detection of Local Anesthetic Ropivacaine by Impedance Method on Polypyrrole-Graphene Oxide

Abstract:

A rapid detection of the local anesthetic ropivacaine was measured by electrochemical impedance method. Polypyrrole (Ppy) and polypyrrole (Ppy)-graphene oxide (GO) composites were prepared by electrochemical polymerization on the gold electrode as the working electrode. The electrochemical properties of the Ppy and Ppy-GO composites electrode were characterized by transmission electron microscopy (TEM), scanning electron microscope (SEM) and Fourier transform infrared spectroscopy (FTIR). Various concentrations from 1 to 20 ppm of ropivacaine were prepared in 0.9% NaCl as the sample solution. Prepared Ppy and Ppy-GO were used as working electrodes, and the sample solution had been measured for a sinusoidal excitation in the frequency range of 100 Hz to 1 MHz. It exhibited the better linearity (R2=0.973) of Ppy/1% GO than Ppy (R2=0.882) from 1 to 20 ppm when the frequency fixed in 100 kHz. All the response and recovery time of 0.1 ppm local anesthetic ropivacaine can be detection in this system within 1 sec, it will be a promising composite material on electrochemical electrode.