Study on Subcritical Water Extraction of Flavonoids from Scutellaria baicalenses

Abstract:

The extraction of baicalin, baicalein, wogonin and wogonoside from Scutellaria Baicalenses was performed using subcritical water. The effects of key operation conditions by varying the temperature (110-160 °C), extraction time (10-90 min), water loadings (2.0-4.0 mL)and particle sizes (>20- <100 mesh) were evaluated. The highest extraction yields of baicalin and wogonoside were obtained at extraction temperature of 160 °C, extraction time of 60 min, water loadings of 4.0 mL and 60-100 mesh. The highest extraction yields of baicalein and wogonin were obtained at extraction temperature of 110 °C, extraction time of 10 min, water loadings of 4.0 mL and 60-100 mesh. The subcritical water extraction was compared with the conventional extraction method. The total extraction yield by SCWE was higher than those obtained using ethanol as the solvent.

• Periodical: Advanced Materials Research (Volume 662)
• Pages: 293-296
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.662.293
• Online since: February 2013
• Authors: Yan Cheng, Jing Liu, Chang An Liu
• Keywords: Baicalein, Baicalin, Scutellaria baicalensis, Subcritical Water, Wogonin, Wogonoside

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