Preparation and Characterization of Magnetic Graphene Oxide

Abstract:

In this paper, the magnetic graphene oxide (Fe₃O₄@GO) has been successfully prepared by decomposition of Iron (III) acetylacetonate in the mixture solution of triethylene glycol and GO. atomic force microscope, TEM, XRD and superconducting quantum interference device were used to characterize the material. The results showed that the magnetic Fe₃O₄ nanoparticles modified graphene oxide has been obtained, and it has superparamagnetism with magnetization saturation of 16.4emu/g. the Fe₃O₄@GO has a good sustained-release performance, and vitro cytotoxicity confirmed that its security for Fe₃O₄@ GO as a potential drug carrier.

• Periodical: Advanced Materials Research (Volumes 774-776)
• Pages: 532-535
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.774-776.532
• Online since: September 2013
• Authors: Yan Shan, Xing Ying Xu, Ke Zheng Chen, Lian Gao
• Keywords: Fe₃O₄, Graphene Oxide, Magnetic

References

[1] W. Wei, G. H. Ma, G. Hu, et al., Preparation of hierarchical hollow CaCO3 particles and the application as anticancer drug carrier. J. Am. Chem. Soc. Vol. 130 (2008), p.15808.

DOI: 10.1021/ja8039585

[2] L. Y. Tang, Y. C. Wang, Y. Li, et al., Shell-detachable micelles based on disulfide -linked block copolymer as potential carrier for intracellular drug delivery. Bioconjugate Chem. Vol. 20 (2009), p.1095.

DOI: 10.1021/bc900144m

[3] S. Santra, C. Kaittanis, J. Grimm, J.M. Perez. Drug/dye-loaded multifunctional iron oxide nanoparticles for combined targeted cancer therapy and dual optical/magnetic resonance imaging . Small. Vol. 5 (2010), p.1862.

DOI: 10.1002/smll.200900389

[4] R. Guo, R. Li, X. L. Li et al., Dual-functional alginic acid hybrid nanospheres for cell imaging and drug delivery. Small. Vol. 5 (2009), p.709.

DOI: 10.1002/smll.200801375

[5] X. Y. Yang, X. Y. Zhang, Z. F. Liu et al., High-efficiency loading and controlled release of doxorubicin hydrochloride on graphene oxide. J. Phys. Chem. C. Vol. 112 (2008), p.17554.

DOI: 10.1021/jp806751k

[6] Y. J. Guo, S. J. Guo, J. T. Ren et al., Cyclodextrin functionalized graphene nanosheets with high supramolecular recognition capability: synthesis and host-guest inclusion for enhanced electrochemical performance. ACS Nano. Vol. 4 (2010), p.4001.

DOI: 10.1021/nn100939n

[7] L. M. Zhang, J. G. Xia, Q. H. Zhao et al., Functional graphene oxide as a nanocarrier for controlled loading and targeted delivery of mixed anticancer drugs. Small. Vol. 6 (2010), p.537.

DOI: 10.1002/smll.200901680

[8] X. Liu, L. Gao, W. Song, K. Ai, L. Lu. Functionalizing metal nanostructured film with grapheme oxide for ultrasensitive detection of aromatic molecules by surface-enhanced raman spectroscopy. ACS Appl. Mater. & Interfaces, Vol. 3 (2011), p.2944.

DOI: 10.1021/am200737b

[9] H. P. Cong, J. J. He, Y. Lu and S. H. Yu, Water-soluble magnetic-functionalized reduced graphene oxide sheets: in situ synthesis and magnetic resonance imaging applications. Small. Vol. 6 (2010), p.169.

DOI: 10.1002/smll.200901360

[10] J. Su, M. H. Cao, L. Ren and C. W. Hu, Fe3O4–graphene nanocomposites with improved lithium storage and magnetism properties. J. Phys. Chem. C. Vol. 115(2011), p.14469.

DOI: 10.1021/jp201666s

[11] X. Y. Yang, X. Y. Zhang, Y. F. Ma et al., Superparamagnetic graphene oxide-Fe3O4 nanoparticles hybrid for controlled targeted drug carriers. J. Meter. Chem. Vol. 19 (2009), p.2710.

DOI: 10.1039/b821416f

[12] S. W. Jr. Hummers, R. E. Offeman, Preparation of graphitic oxide. J. Am. Chem. Soc. Vol. 80 (1958), p.1339.

DOI: 10.1021/ja01539a017

[13] N. I. Kovtyukhova, P. J. Ollivier, B. R. Martin et al., Layer-by-layer assembly of ultrathin composite films from micron-sized graphite oxide sheets and polycations. Chem. Mater. Vol. 11(1999), p.771.

DOI: 10.1021/cm981085u

[14] N. Kohler, C. Sun, J. Wang et al., Methotrexate-modified superparamagnetic nanoparticles and their intracellular uptake into human cancer cells. Langmuir. Vol. 21(2005), p.8858.

DOI: 10.1021/la0503451