Electrospun Polycaprolactone Fiber Mats as Carriers for Tannic Acid

Abstract:

Fiber mats of polycapolactone (PCL) containing tannic acid were prepared by electrospinning from tannic acid-containing PCL solutions in 1:1 v/v dichloromethane/ N,N-dimethylformamide. The base PCL solution was prepared at 12%w/v and the different amounts of tannic acid (5, 10, and 20% w/w based on weight of PCL) were added in the PCL solution. For 5% and 10% tannic acid-loaded PCL fiber mats, the fibers were smooth, with the average fiber diameter of 1.02 and 1.26 μm, respectively. The amounts of water retention and release characteristics of tannic acid-loaded PCL fiber mats and tannic acid-loaded as-cast PCL films in acetate buffer (pH=5.5) at 30°C were studied. Tannic acid-loaded PCL fiber mats exhibited greater amount of water retention and tannic acid released than the tannic acid-loaded as-cast PCL films.

• Periodical: Advanced Materials Research (Volumes 774-776)
• Pages: 896-900
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.774-776.896
• Online since: September 2013
• Authors: Patcharaporn Thitiwongsawet, Nitiya Wichapeng, Adjimaporn Waiyaroj
• Keywords: Drug Delivery, Electro-Spinning, Polycaprolactone, Tannic Acid

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