Monoamine Oxidase Inhibitory Activity of the Total Alkaloid and Organic Acid from Chinese Herbal Medicines

Zhong Duo Yang; Jin Ren; Zong Mei Shu

doi:10.4028/www.scientific.net/AMR.781-784.899

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 781-784Monoamine Oxidase Inhibitory Activity of the Total...

Monoamine Oxidase Inhibitory Activity of the Total Alkaloid and Organic Acid from Chinese Herbal Medicines

Abstract:

The aim of this study was to search for potential monoamine oxidase (MAO) inhibitors from Chinese herbal medicine. The organic acid extracts of 34 and the total alkaloidal extracts of 30 traditional Chinese medicines were tested for their MAO inhibitory activities. The results showed that the organic acid extracts of Liquidambar formosana, Pharbitis nil, Punica granatum and alkaloid extracts of Coptis chinensis exhibited the most potent inhibition on MAO and their concentration that inhibited 50% of MAO activity (IC50) values less than 10 μg/mL.

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Periodical:

Advanced Materials Research (Volumes 781-784)

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899-902

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https://doi.org/10.4028/www.scientific.net/AMR.781-784.899

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Online since:

September 2013

Authors:

Zhong Duo Yang, Jin Ren, Zong Mei Shu

Keywords:

Alkaloid, Chinese Herbal Medicine, MAO Inhibitors, Organic Acid

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