A Novel Strategy for the Synthesis of Azetidine

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Abstract:

A novel method for the synthesis of azetidine via phosphoramidate intermediate has been developed. In the key step, cleavage of the PN bond in azetidin-1-ylphosporamidate with hydrochloric acid furnished a high-yielding conversion to azetidine hydrochloride.

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135-138

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October 2013

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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