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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 830One-Pot Synthesis of...

One-Pot Synthesis of P¹,P²-Diaciclovir-5'-Diphosphate from Aciclovir 5'-H-Phosphonate

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Abstract:

P¹,P²-Diaciclovir-5'-diphosphate has been synthesized efficiently from aciclovir 5'-H-phosphonate monoester via a one-pot reaction. This method features easily accessible H-phosphonate starting material, short reaction time, and good isolated yield.

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Advanced Research on Material Engineering, Chemistry, Bioinformatics III

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Periodical:

Advanced Materials Research (Volume 830)

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222-225

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.830.222

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Online since:

October 2013

Authors:

Hai Xin Ding, Si Liu, Shan Shan Gong*, Qi Sun

Keywords:

Antiviral Nucleoside, Dinucleoside Diphosphate, H-Phosphonate, Phosphoramidate, Prodrug

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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