Web-Like Nanofibers for Improving Fibroblast Growth

Article Preview

Abstract:

During electrospinning process, charged web jets solidify with solvent evaporation and form two-dimensional (2D) web-like nanofibers on the collecting plate. In this paper, Poly [(lactic acid)-co-(glycolic acid)] (PLGA) solutions are used to produce different 2D web-like nanofibers, which can mimic the physical features of natural extracellular matrix (ECM) at the nanoscale and improve fibroblast growth. According to mass conservation, the possible mechanisms for the web formation are investigated.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

53-57

Citation:

Online since:

November 2013

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] D. Kimmer, P. Slobodian, D. Petras, M. Zatloukal, R. Olejnik, P. Saha, Polyurethane/Multiwalled Carbon Nanotube Nanowebs Prepared by an Electrospinning Process, J. Appl. Polym. Sci. 111 (2009) 2711–2714.

DOI: 10.1002/app.29238

Google Scholar

[2] H.R. Pant, M.P. Bajgai, K.T. Nam, K.H. Chu, S.J. Park, H.Y. Kim, Formation of electrospun nylon-6/methoxy poly(ethylene glycol) oligomer spider-wave nanofibers, Mater. Lett. 64 (2010) 2087–2090.

DOI: 10.1016/j.matlet.2010.06.047

Google Scholar

[3] F.J. Liu, R. Guo, M.W. Shen, X.Y. Cao, X.M. Mo, S.Y. Wang, X.Y. Shi, Effect of the Porous Microstructures of Poly(lactic-co-glycolic acid)/Carbon Nanotube Composites on the Growth of Fibroblast Cells, Soft Materials. 8 (2010) 239-253.

DOI: 10.1080/1539445x.2010.495620

Google Scholar

[4] J.H. He, Effect of temperature on metabolic rates of virus and host cells, Curr. Opin. Biotech. 22 (2011) S43-S44.

Google Scholar