Refining the Very Important Value of Mass to Charge Ratio from Traditional Chinese Medicine' Nature Data

Abstract:

The research for Chinese herbs warm and cold natures classification is a significative thing for clinical. The paper put forward refining the very important value of mass to charge ratio (M/Z) from Traditional Chinese Medicine' Nature data using orthogonal signal correction-orthogonal partial least squares-discriminant analysis (OSC-OPLS/O2PLS-DA) after normalization. The first , data standardizing for the metabolites sample spaces data; The second, Reducing dimensions for the metabolites sample spaces data using OSC; the third, distinguish TCM' nature using OPLS/O2PLS-DA ;The fourth, gain the very important value of Mass to charge ratio for TCM' nature; The fifth, According to the necessary of the research, repeat the fourth step and the fifth step, and refine the M/Z.The model was proved to be feasible and effective after tested with 6 types warm natures herbs, 6 types cold natures herbs.

• Periodical: Advanced Materials Research (Volumes 864-867)
• Pages: 508-511
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.864-867.508
• Online since: December 2013
• Authors: Bin Nie*, Jian Qiang Du, Zhuo Wang, Ri Yue Yu, Guo Liang Xu
• Keywords: M/Z, OPLS/O2PLS-DA, OSC, Refining, Traditional Chinese Medicine

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