Two New Natural Products from the Roots of Raphanus sativus L.

Shun Bin Wu; Feng Wang; Xiao Bao Jin; Tao Liu; Li Rong Wu; Wei Wang; Dan Mei; Zhong Zheng; Jia Yong Zhu

doi:10.4028/www.scientific.net/AMR.884-885.548

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 884-885Two New Natural Products from the Roots of...

Two New Natural Products from the Roots of Raphanus sativus L.

Abstract:

The roots of Raphanus sativus L., also called radish, has been used as a traditional anti-migraine drug in China for hundreds of years. However, its bioactive substances and pharmacological mechanism were still not very clear. In this study, two new natural products were isolated from the roots of Raphanus sativus L. by successive chromatographic procedures, such as open silica gel, Sephadex LH-20 and RP-18 column chromatograph. The structures of isolated compounds were elucidated as Cis-(1-methylazetidin-2-yl) methanol and cyclo- (4-methyl-Val-4-methyl-Val) on the basis of spectral data analysis, including MS and NMR (¹H-NMR, ¹³C-NMR, NOESY, HSQC and HMBC). The new natural products would be potential candidates for early anti-migraine drug study.

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Periodical:

Advanced Materials Research (Volumes 884-885)

Pages:

548-552

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.884-885.548

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Online since:

January 2014

Authors:

Shun Bin Wu, Feng Wang, Xiao Bao Jin, Tao Liu, Li Rong Wu, Wei Wang, Dan Mei, Zhong Zheng, Jia Yong Zhu*

Keywords:

New Natural Products, Raphanus sativus l, Spectroscopic Characterization

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