Magnetic Nanoparticle-Based Biosensors for the Sensitive and Selective Detection of Urine Glucose

Abstract:

In this work, a diagnostic application was performed by utilizing magnetic nanoparticles for the bio-sensing. A novel Fe₃O₄ nanostructure was synthesized in this paper using a simple hydrothermal method, the Fe₃O₄ nanoparticles are successfully controlled to provide a more dynamic site for catalytic reaction. FTIR-analysis, scanning electron microscopy (SEM), X-ray diffraction (XRD) was used to examine the morphology of the synthesized nanoparticles. The findings showed that a unique Fe₃O₄ nanostructure was obtained nanoparticles confined in nanosphere. The relative catalytic kinetics of Fe₃O₄ nanostructure has followed Michaelis–Menten behaviours, according to an analysis of peroxidase-like activity. An effective approach for colorimetric sensing of glucose was formulated on the bases of efficient peroxidase-mimicking activity of Fe₃O₄ nanoparticles. The synthesized Fe₃O₄ nanoparticles are very hopeful for the application of bio-sensors.

• Periodical: Advances in Science and Technology (Volume 117)
• Pages: 79-84
• DOI: https://doi.org/10.4028/p-45cyly
• Online since: August 2022
• Authors: Tousief Irshad Ahmed, Reegan Aruldoss, Bhasker Pant, Indhumathi Kulandhaisamy, R. Raffik*, Ganesh Bhaskarrao Sonawane
• Keywords: Biosensor, Fe₃O₄, Magnetic Property, Urine Glucose

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