TiO₂ Nanoparticles Based Peroxidase Mimics for Colorimetric Sensing of Cholesterol and Hydrogen Peroxide

Abstract:

It's still a challenge to detect cholesterol more rapidly and easily. As a result, using a colorimetric sensor to detect cholesterol may result in the development of a ready-to-use. This research shows how a TiO₂ nanoparticles may be utilized as a peroxidase mimic to detect H₂O₂ and free cholesterol. The TiO₂ Nanoparticles was carefully studied in terms of structural, morphological, and functional characteristics. In the existence of cholesterol oxidase, and the proposed approach comprises detecting H₂O₂ produced during cholesterol oxidation. The TiO₂ nanoparticles sensor has shown good cholesterol detection sensitivity with a LOD as low as 0.061 M and a linear response in the 0.1 mM to 50 mM range.

• Periodical: Advances in Science and Technology (Volume 117)
• Pages: 85-90
• DOI: https://doi.org/10.4028/p-7in58j
• Online since: August 2022
• Authors: R. Rathinam*, Devesh Pratap Singh, Arjun Dutta, S. Rudresha, Shaikh Rajesh Ali, Pratik Chatterjee
• Keywords: Biomarker, Cholestrol Detection, Hydrogen Peroxide, TiO₂

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