This paper briefly introduces the nano-bio related-research being carried out in our research group. The work is based on a fusion of neuroscience and bio-molecular science with nanotechnology. This interdisciplinary research is extremely promising for creating a new technology and developing a new knowledge. Nano-bio research could be a key to understanding the signal processing mechanism that lies behind memory and the learning system in our brain. Developing a novel biocompatible device that runs with biological functions is one of our research goals.