Nonspherical Gold Nanoparticles as Bright Light Scattering Labels with Narrow Plasmon Lines

Vladimir A. Vinokurov; Alexander V. Muradov; Michael Getmanskiy; Le Qiu; Edward Vitkin; Irving Itzkan; Lev T. Perelman

doi:10.4028/www.scientific.net/AST.86.51

Paper Titles

Sol-Gel Synthesis and Characterization of Lanthanide-Substituted Nanostructured Calcium Hydroxyapatite
p.22

Apatite Coating on Titanium Samples Obtained by Powder Metallurgy
p.28

Understanding In Vivo Abrasion Fatigue of Common Suture Materials Used in Arthroscopic and Open Shoulder Surgery
p.34

Nanotechnology Enabled In Situ Orthopaedic Sensors for Personalized Medicine
p.40

Nonspherical Gold Nanoparticles as Bright Light Scattering Labels with Narrow Plasmon Lines
p.51

Movable Polyrotaxane Surfaces for Modulating Cellular Adhesion via Specific RGD-Integrin Binding
p.59

Application of α-TCP/HAp Functionally Graded Porous Beads for Bone Regenerative Scaffold
p.63

Fabrication of Scaffold for Bone Regeneration by Taylor Made Stereolithography
p.70

Design and Development of Light-Sensitive Chitosan-Based Nanocarriers for Gene Delivery
p.75

HomeAdvances in Science and TechnologyAdvances in Science and Technology Vol. 86Nonspherical Gold Nanoparticles as Bright Light...

Nonspherical Gold Nanoparticles as Bright Light Scattering Labels with Narrow Plasmon Lines

Abstract:

In this paper we discuss the potential of nonspherical gold nanoparticles to serve as extremely bright light scattering labels for the detection of disease through several centimeters of tissue in humans in vivo. However, attempts to realize this important potential of gold nanoparticles have been limited by the broad spectroscopic linewidths usually observed. We identify the origin of this broadening as inhomogeneous broadening due to the extreme sensitivity of the surface plasmon resonance to the nanoparticle aspect ratio.

You might also be interested in these eBooks

Biomedical Applications of Smart Technologies

View Preview

Info:

Periodical:

Advances in Science and Technology (Volume 86)

Pages:

51-58

DOI:

https://doi.org/10.4028/www.scientific.net/AST.86.51

Citation:

Cite this paper

Online since:

September 2012

Authors:

Vladimir A. Vinokurov, Alexander V. Muradov, Michael Getmanskiy, Le Qiu, Edward Vitkin, Irving Itzkan, Lev T. Perelman

Keywords:

Absorption, Label, Light Scattering, Nanoparticle, Plasmon, Spectroscopy

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] P. C. Waterman, Matrix formulation FO electromagnetic scattering, Proc. IEEE 53 (1965) 805.

Google Scholar

[2] P. Debye, The heliograph of spheres of any material, Ann. Phys. 30 (1909) 57-136.

Google Scholar

[3] L. Qiu, T. A. Larson, D. K. Smith, E. Vitkin, M. D. Modell, B. A. Korgel, K. V. Sokolov, E. B. Hanlon, I. Itzkan, and L. T. Perelman, Observation of plasmon line broadening in single gold nanorods, Appl. Phys. Lett. 93 (2008) 153106-1-4.

DOI: 10.1063/1.2995982

Google Scholar

[4] Qiu L, Larson TA, Smith DK, Vitkin E, Zhang S, Modell MD, Hanlon EB, Itzkan I, Korgel BA, Sokolov KV, and Perelman LT. Single Gold Nanorod Detection using Confocal Light Absorption and Scattering Spectroscopy, , IEEE J. Sel. Top. Quant. Elect. 13 (2007).

DOI: 10.1109/jstqe.2007.910802

Google Scholar

[5] L. D. Landau and E. M. Lifshitz, Electrodynamics of Continuous Media, Pergamon Press, Oxford, UK, 2nd edition, (1984).

Google Scholar

[6] S. W. Prescott and P. Mulvaney, Gold nanorod extinction spectra, , J. Appl. Phys. 99 (2006), 123504.

DOI: 10.1063/1.2936980

Google Scholar

[7] C. F. Bohren and D. R. Huffman, Absorption and Scattering of Light by Small Particles, John Wiley & Sons, New York, (1983).

Google Scholar

[8] I. Itzkan, L. Qiu, H. Fang, M. M. Zaman, E. Vitkin, L. C. Ghiran, S. Salahuddin, M. Modell, C. Andersson, L. M. Kimerer, P. B. Cipolloni, K-H. Lim, S. D. Freedman, I. Bigio, B. P. Sachs, E. B. Hanlon, and L. T. Perelman, Confocal light absorption & scattering spectroscopic (CLASS) microscopy monitors organelles in live cells with no exogenous labels, Proc. Natl. Acad. Sci. USA 104 (2007).

DOI: 10.1073/pnas.0708669104

Google Scholar

[9] P. B. Johnson and R. W. Christy, Optical constants of noble metals, Phys. Rev. B, 6 (1972) 4370-4379.

DOI: 10.1103/physrevb.6.4370

Google Scholar