Animal implants experiments are obligatory when developing human artificial hard tissues, such as bio-ceramics. Optical microscope is often used to inspect implant slices but may destroy original status when slicing up. We tried 3D high resolution CT to nondestructively study biocompatibility and degradation of bio-ceramics implants. 3D CT provides 3D structure information. Typical pixel size of 3D high resolution CT is 50 microns. Generally, implants differs with tissues in density and structure, on basis of which we can identify details with CT slice. Experiments of bio-ceramic implanted into rabbit hip are also showed. Interaction could be identified at interface between implant and tissue.