In Vitro Characterization of Bioactive Glasses
In vitro behavior of 30 new glasses in the system Na2O-K2O-MgO-CaO-B2O3 -P2O5-SiO2 was investigated by immersing them into a simulated body fluid for 4 to168 hours. This study involved the observation of both the changes in the properties of the immersion solution and on the glasses surface after immersion. In vitro reactivity was different for each experimental glass depending on its chemical composition. By comparing these glasses to four established bioactive glasses showing different in vivo bioactivity, a fast estimation of the bioactivity of glasses can be done; thereby the optimization of bioactive glasses for various clinical applications can be developed.
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
D. Zhang et al., "In Vitro Characterization of Bioactive Glasses", Key Engineering Materials, Vols. 284-286, pp. 481-484, 2005