Preparation of Cellulose-Carbonate Apatite Composites through Mechanochemical Reaction

Akihiko Yoshida; Toshiki Miyazaki; Eiichi Ishida; Masahiro Ashizuka

doi:10.4028/www.scientific.net/KEM.284-286.855

Paper Titles

Comparative Investigation of Coprecipitation and In-Situ Synthesis of Nanohydroxyapatite/Collagen Composite
p.839

Growth of Normal Human Osteoblast Cells on Hydroxyapatite/Titanium Alloy Composites Formed by Implantation of Hydroxyapatite Granules into Titanium Alloy
p.843

The Effect of Calcium Aluminate Bone Cement Incorporating LiF-Maleic Acid on the Bone Regeneration of 1-Wall Intrabony Defects in Beagle Dogs
p.847

Effect of Calcium Phosphate Glass Scaffold with Chitosan Membrane on the Healing of Alveolar Bone in 1 Wall Intrabony Defect in the Beagle Dogs
p.851

Preparation of Cellulose-Carbonate Apatite Composites through Mechanochemical Reaction
p.855

Preparation and In Vitro Evaluation of Radioactive Calcium-Phosphate Micron-Sized Particles for Internal Radiotherapy of Hepatoma
p.859

Development of Bioactive Alumina-Wollastonite Composite by Electrophoretic Deposition
p.863

TCP-HA Granules and Impacted Morselized Cancellous Bone Graft Mixes for Acetabular Reconstruction with the Bone Impaction Grafting Technique. A Loaded and Critical Sized Defect Model in the Goat
p.869

Erosion of Dental Glass Infiltrated Aluminum Ceramics
p.873

HomeKey Engineering MaterialsKey Engineering Materials Vols. 284-286Preparation of Cellulose-Carbonate Apatite...

Preparation of Cellulose-Carbonate Apatite Composites through Mechanochemical Reaction

Abstract:

Organic-inorganic composites composed of organic polymer and carbonate hydroxyapatite (CHAp) would be useful bone substitute materials exhibiting low young’s modulus and bone-bonding bioactivity. In this work, such a composite was synthesized from cellulose (CEL)and CHAp through mechanochemical reaction. Homogeneous bulk CEL-CHAp composites were obtained when poly( ε-caprolactone) (PCL) was added as plasticizer with PCL/(PCL+CEL) weight ratio of 20 wt% or less. The CEL-CHAp composites contained B-type CHAp in inorganic phase. The composites with (CEL+PCL)/(CHAp) weight ratio = 20/80 and 10/90 kept the shape in simulated body fluid (SBF), and showed apatite formation after soaking in SBF. Therefore, the CEL-CHAp composites are expected to be materials with low young’s modulus and bioactivity.