Novel Prosthesis Using Silk Fibroin for Small Caliber Vascular

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Abstract:

A novel prosthesis using silk fibroin with blending heparin and sulfonated silk fibroin was studied. Anticoagulation activities of heparin/silk fibroin and sulfonated silk fibroin/silk fibroin vascular and mechanical property results showed that heparin/silk fibroin and sulfonated silk fibroin/silk fibroin vascular could meet the requirement of small caliber grafts. This study indicated that silk fibroin could be used for developing tissue engineering biological vascular grafts that could use for human coronary or low extremity artery bypasses.

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Key Engineering Materials (Volumes 288-289)

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461-464

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June 2005

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© 2005 Trans Tech Publications Ltd. All Rights Reserved

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