Surface Characteristics and Osteoinductivity of Biphasic Calcium Phosphate Ceramics with Different Sintering Temperature
Calcium phosphate (Ca-P) biomaterials have been proved to show osteoinductivity, however the affecting factors and mechanism are still unclear now. In this study, the surface characteristics of biphasic Ca-P ceramics (hydroxyapatite/tricalcium phosphate; HA/TCP) sintered at the distinct temperature were investigated and the mechanism of the osteoinductivity was discussed. The osteoinductivity of HA/TCP ceramics increased with decreasing the sintering temperature. The different surface micro-structure resulted from different sintering temperature includes phase composition, surface micro-structure, and surface potential. These characteristics should be the important factors affecting osteoinductivity.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
H. S. Fan et al., "Surface Characteristics and Osteoinductivity of Biphasic Calcium Phosphate Ceramics with Different Sintering Temperature ", Key Engineering Materials, Vols. 309-311, pp. 1299-1302, 2006