Chemicovector Effect of Nano-Size-Hydroxyapatite Doped YSZ Ceramics on Apatite Formability in SBF
To produce ceramics with high mechanical strength and bioactivity, we developed the little amount of nano-sized hydroxyapatite (HA)-doped zirconia composite ceramics (nanoHA-Z). The bioactivity of the nanoHA-Z was studied by in vitro estimation with simulated body fluid (SBF). Scanning electron microscopy observation showed deposited bone-like apatite layer entire covering the surface of nanoHA-Z ceramics in SBF. The enhanced apatite formability was attributed to higher Ca and PO4 concentrations in the vicinities of the nanoHA-Z surfaces due to the dissolution of the β-tricalcium phosphate decomposed from the added HA. Utilization of Chemicovector effect was proved to be one of the powerful approaches for improvement method of biomaterials.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
S. Kishi et al., "Chemicovector Effect of Nano-Size-Hydroxyapatite Doped YSZ Ceramics on Apatite Formability in SBF", Key Engineering Materials, Vols. 309-311, pp. 589-592, 2006