Bovine Serum Albumin Adsorption on Hydroxyapatite and Biphasic Calcium Phosphate and the Correlation with Zeta Potentials and Wettability

Xiang Dong Zhu; Hong Song Fan; Chao Yong Zhao; Toshiyuki Ikoma; M. Tanaka; Ji Yong Chen; Xing Dong Zhang

doi:10.4028/www.scientific.net/KEM.309-311.73

Paper Titles

Preparation of Hydroxyapatite Ceramics by Hydrothermal Hot-Pressing Technique
p.57

Neutron Characterisation of Hydroxyapatite Bioceramics
p.61

Preparation and Characterization of Hydroxyapatite Microspheres with Hollow Core and Mesoporous Shell
p.65

Progress of Structural Elucidation of Amorphous Calcium Phosphate(ACP)and Hydroxyapatite (HAp): Disorder and Surfaces as Seen by Solid State NMR
p.69

Bovine Serum Albumin Adsorption on Hydroxyapatite and Biphasic Calcium Phosphate and the Correlation with Zeta Potentials and Wettability
p.73

Mesoporous Structure and Protein Adsorption Property of c-Axis Oriented Apatite Aggregates
p.77

Protein Adsorption Ability of Porous Hydroxyapatite Microparticle with Metal Ions
p.81

Effect of Mg on Surface Roughness and Protein Content of Protein-Apatite Composite Layers
p.85

Effects of Through-holes' Diameter on Initial Cell Attachment and Cell Proliferation
p.89

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Bovine Serum Albumin Adsorption on Hydroxyapatite and Biphasic Calcium Phosphate and the Correlation with Zeta Potentials and Wettability

Abstract:

Studying on the interaction between proteins and calcium phosphate implants is one of the basic subjects in biomaterials science and engineering. In this work, zeta potentials and contact angles of hydroxyapatite (HA) and biphasic calcium phosphate (BCP) ceramics were measured, and the adsorption behaviors of bovine serum albumin (BSA) on the surfaces were investigated. The adsorption isotherms of BSA on both ceramics follow the Langmuir type, however, BCP shows higher BSA adsorption ability. The differences of contact angles and zeta potentials in HA and BCP are the key factors to determine their ability to bind BSA molecules.