Microstructure and In Vitro Bioactivities of HA/Ti Composites Prepared by Hot Isostatic Pressing

Hua Ke; Yu Zhou; De Chang Jia; Cong Qin Ning

doi:10.4028/www.scientific.net/KEM.336-338.1715

Paper Titles

Biomimetic Synthesis of PEC-HA Composite Analogous to Bone
p.1699

Development of Ultrafine Fibrous Hydroxyapatite/Polymer Scaffold by Electrospinning
p.1703

Experimental Study of Biomimetic Mineralization on the Surface of Piezoelectric Pulp-Cap Film
p.1707

Bisphosphonate Pamidronate Modifying Hydroxyapatite Bioceramics for Hard Tissue Repair
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Microstructure and In Vitro Bioactivities of HA/Ti Composites Prepared by Hot Isostatic Pressing
p.1715

Improvement in the Sensitivity of the Response of Diamond Thin Films to X-Ray
p.1718

Microstructure of Ceramic Layer in Composite Pipe Made by SHS-Gravitational Process
p.1722

Microstructure and Properties of In Situ Synthesis of TiC Particle Reinforced Composite Coating by Induction Cladding
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Adhesion of Diamond Film to Co- Deficient Cemented Tungsten Carbide Substrate
p.1728

HomeKey Engineering MaterialsKey Engineering Materials Vols. 336-338Microstructure and In Vitro Bioactivities of HA/Ti...

Microstructure and In Vitro Bioactivities of HA/Ti Composites Prepared by Hot Isostatic Pressing

Abstract:

Hydroxyapatite (HA)/titanium (Ti) composites were successfully fabricated by hot isostatic pressing at 850°C. The microstructure of 7T2HB (70Ti+20HA+10Bioglass, Vol. %) composites were systematically investigated. The main constituents of the composites are hydroxyapatite and titanium. A simulated body fluid (SBF) with the same ion concentrations as those of human plasma and pH value of 7.4 is selected to evaluate the in vitro biological properties of the composites. After 2-week immersion in SBF, the bioactive apatite formed a very dense film on the surface of the composites. The dissolution of CaO and Ca-P compounds in SBF improves the growth of apatite on the surface of the composites.

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Periodical:

Key Engineering Materials (Volumes 336-338)

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1715-1717

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https://doi.org/10.4028/www.scientific.net/KEM.336-338.1715

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Online since:

April 2007

Authors:

Hua Ke, Yu Zhou, De Chang Jia, Cong Qin Ning

Keywords:

Bioproperty, Hydroxyapatite (HAP), Simulated Body Fluid (SBF)

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References

[1] J. C. Elliott, P. E. Mackie, and R. A. Young: Science Vol 180 (1973) p.1055.

Google Scholar

[2] L. Hong, H. C. Xu, and K. De Groot: J. Biomed Mater. Res. Vol 26 (1992) p.7.

Google Scholar

[3] J. T. Edwards, J. B. Brunski, and H. W. Higuchi : J. Biomed Mater. Res. Vol 36 (1997) p.454.

Google Scholar

[4] K. E. Healy and P. Ducheyne: J. Biomed Mater. Res. Vol 26 (1992) p.319.

Google Scholar

[5] A. Nanci, J. D. Wuest, L. Peru, P. Brunet, V. Sharma, S. Zalzal, and M. D. McKee: J. Biomed Mater. Res. Vol 40 (1998) p.324.

DOI: 10.1002/(sici)1097-4636(199805)40:2<324::aid-jbm18>3.0.co;2-l

Google Scholar

[6] X. B. Zheng, M. H. Hang, and C. X. Ding: Biomaterials Vol 21 (2000) p.841.

Google Scholar

[7] L. L. Hench: J. Am. Ceram Soc. Vol 81 (1998) p.1705.

Google Scholar

[8] Jansen J, J. P. C. M. Vande Waerden, J. G. C. Wolke, and K. De Groot: J. Biomed Mater. Res. Vol 25 (1991) p.97.

Google Scholar

[9] P. Ducheyne and G. W. Hastings: Metal and Ceramic Biomaterials. In: Strength and surface, vol. II. Boca Raton: CRC Press (1984) p.144.

Google Scholar

[10] C. Q. Ning: Mechanical Properties and Biological Behavior of Ti/HA Biocomposites (Ph.D. Thesis, P.R. China 2001).

Google Scholar

[11] C. Ohtsuki, T. Kokubo, and T. Yamamuro: J. Non-Cryst. Solids. Vol 143 (1992) p.84.

Google Scholar

[12] C. Q. Ning and Y. Zhou: Biomaterials Vol 25 (2004), p.3379.

Google Scholar

[13] C. Q. Ning and Y. Zhou: Biomaterials Vol 23 (2002), p.2909 Energy (keV) Energy (keV) Fig. 4. EDXA spectra on the surfaces of the composite after various immersion times: (a) 1 day (b) 14 days.

Google Scholar