The Role of Endothelial Cells Differentiated from Bone Marrow Stem Cells in Cartilage and Bone Regeneration
Mesenchymal stem cells (MSCs) from bone marrow seem to be the one of best candidates to regenerate injured tissue. However, recent advances in application of MSCs toward large tissue regeneration are faced with lack of vascularity. In this study, endothelial cells differentiated from MSCs were applied for constructing tissue-engineered bone and cartilage. It was found that endothelial cells from MSCs play an important role of providing vasculature.
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
H. Y. Chung et al., "The Role of Endothelial Cells Differentiated from Bone Marrow Stem Cells in Cartilage and Bone Regeneration", Key Engineering Materials, Vols. 342-343, pp. 193-196, 2007