Preparation and In Vitro Evaluation of Nerve Conduit Using Electro-Spun Biodegradable Polymers

Abstract:

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In this study, we find out the possibilities to make conduit for nerve regeneration using biodegradable polymers, which have enough mechanical strength in surgery. Cell adhesion (PC12) behaviors about various nerve conduits have not great difference compared to control. This is regarded due to specific structure of nerve conduits formed nano-fibers. In the case of PPD, we observed better phenotype of adhered cell than PLGA samples. Also, PPD-PLGA bi-layered nerve conduits were more effective than PLGA nerve conduit for in vitro evaluation.

Info:

Periodical:

Key Engineering Materials (Volumes 342-343)

Edited by:

Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon

Pages:

325-328

DOI:

10.4028/www.scientific.net/KEM.342-343.325

Citation:

H. K. Bae et al., "Preparation and In Vitro Evaluation of Nerve Conduit Using Electro-Spun Biodegradable Polymers ", Key Engineering Materials, Vols. 342-343, pp. 325-328, 2007

Online since:

July 2007

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Price:

$35.00

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