Preparation and In Vitro Evaluation of Nerve Conduit Using Electro-Spun Biodegradable Polymers

Hong Ki Bae; Chong Pyong Chung; Dong June Chung

doi:10.4028/www.scientific.net/KEM.342-343.325

Paper Titles

In Vitro Studies of Macrophage Biological Behavior on Cardiovascular Biomaterials
p.309

In-Stent Restenosis in the Rabbit Common Carotid Arteries Organ Culture
p.313

Effect of Rapamycin/Curcumin Co-Loaded Poly(Lactide-Co-Glycolide) Films on Blood Compatibility and Vascular Smooth Muscle Cell Proliferation
p.317

Characterization of the Gel-Spun Tubular Scaffold for Cardiovascular Tissue Engineering
p.321

Preparation and In Vitro Evaluation of Nerve Conduit Using Electro-Spun Biodegradable Polymers
p.325

Chitosan/Heparin Polyelectrolyte Complex Nanoparticles (100~200nm) Covalently Bonded with PEI for Enhancement of Chondrogenic Phenotype
p.329

Optimization of Scaffold for a Successful Hydrogel-Seeding Method for Vascular Tissue Engineering
p.333

Enhancement of the Strength and Stability of Ultraviolet-Irradiated Acellular Dermal Matrix by Adding Glucose
p.337

Synthesis of Biodegradable Scaffold from Nano Fibers and Evaluation of Protein Adsorption Behaviors on its Surface
p.341

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Preparation and In Vitro Evaluation of Nerve Conduit Using Electro-Spun Biodegradable Polymers

Abstract:

In this study, we find out the possibilities to make conduit for nerve regeneration using biodegradable polymers, which have enough mechanical strength in surgery. Cell adhesion (PC12) behaviors about various nerve conduits have not great difference compared to control. This is regarded due to specific structure of nerve conduits formed nano-fibers. In the case of PPD, we observed better phenotype of adhered cell than PLGA samples. Also, PPD-PLGA bi-layered nerve conduits were more effective than PLGA nerve conduit for in vitro evaluation.