Effect of Hydroxyapatite-Tricalcium Phosphate Micro-Particles on the Cellular Interaction of In Situ Hyaluronic Acid-Poly(Ethylene Oxide) Hydrogel

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In vitro cell behaviors of calvarial osteoblasts (MC3T3) were evaluated by seeding them on both the surface and inside of in situ hyaluronic acid-poly(ethylene oxide) (HA-PEO) hydrogel, either after or before incorporation of mixture micro-particles of hydroxyapatite-β-tricalcium phosphate on/inside the hydrogel, respectively. Cellular behaviors such as adhesion and proliferation on the surface and inside the gel were evaluated with light microscopy and a microplate reader by focusing on the interactions of cell-HA-PEO as well as cell-hydroxyapatitetricalcium phosphate micro-particle surface in the gel. Cell adhesion and spreading seemed to be enhanced by supplying the micro-particles to the inside the HA-PEO hydrogel, compared to the results of the HA-PEO hydrogel itself.

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Periodical:

Key Engineering Materials (Volumes 342-343)

Edited by:

Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon

Pages:

765-768

Citation:

M. S. Kim et al., "Effect of Hydroxyapatite-Tricalcium Phosphate Micro-Particles on the Cellular Interaction of In Situ Hyaluronic Acid-Poly(Ethylene Oxide) Hydrogel", Key Engineering Materials, Vols. 342-343, pp. 765-768, 2007

Online since:

July 2007

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$38.00

[1] M. Heggli, N. Tirelli, A. Zisch, J.A. Hubbell: Bioconjugate Chem. Vol. 14 (2003), p.967.

[2] L.A. Fortier, A.J. Nixon, H.O. Mohammed, G. Lust: Am. J. Vet. Res. Vol. 58 (1997), p.66.

[3] S.J. Bryant, K.S. Anseth: J. Biomed. Mater. Res. Vol. 59 (2001), p.63.

[4] I. Noh, G.W. Kim, Y.J. Choi, M.S. Kim, Y. Park, K.B. Lee, I.S. Kim, S.J. Hwang and G. Tae: Biomed. Mat. Vol. 1 (2006).

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