The combustor chamber, diffuser and nozzle are the main components of the ramjet engine. In this study, the thermal strength of the combustion chamber of the ramjet engine was evaluated. The combustion chamber consists of an Inconel alloy 718 liner and a 17-4Ph stainless steel housing. The liner is rapidly heated to a high temperature. The heated liner is cooled with a film cooling method that forms a cold boundary layer to separate the hot gas from the surface of the liner. The thermo-structural analysis is evaluated the thermal strength of super alloy structure with various thermal insulation performances by finite element method with code MSC/Nastran. The result of the analysis is compared with accelerated stress rupture test. The experiment is performed to get safety design and estimate actually life-time for combustor chamber under high temperature. In general, the work in this paper is helpful to further improve the understanding and evaluation of thermal strength of the super alloy structure with various thermal insulation performances.