Comparison of HAp and β-TCP in BMP-2 Dose-Response and Release Study


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The aim of this study is to investigate in vivo local BMP-2 PK and bone induction in two bioceramics blocks (HAp, β-TCP), based on different composition and surface structures. We estimated the in vivo release profile of 125I–labeled BMP-2 and bone induction of hard tissues histologically. β-TCP is more effective for both BMP-2 retention and bone induction, compared to HAp, in the ectopic model.



Key Engineering Materials (Volumes 361-363)

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Edited by:

Guy Daculsi and Pierre Layrolle




J. Tazaki et al., "Comparison of HAp and β-TCP in BMP-2 Dose-Response and Release Study", Key Engineering Materials, Vols. 361-363, pp. 1033-1036, 2008

Online since:

November 2007




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