Mechanical Properties of Living Cells: Interaction of the Adherent Endothelial Cell and the Fluid Shear Flow

Xiao Heng Liu; Hong Mei Yin; Yi Lai; Long Juan Xue

doi:10.4028/www.scientific.net/KEM.361-363.1157

Paper Titles

Effect of Sintering Process of HA/TCP Bioceramics on Microstructure, Dissolution, Cell Proliferation and Bone Ingrowth
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Characterization of Bone Cell Behaviors on Collagen Grafted Hydroxyapatite Surfaces
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Isolation Yield and Osteogenic Potential of Human Bone Marrow Stromal Cells are Maintained Irrespective of Age or Gender
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Expression Patterns of Cell Surface Molecules on Human Bone Marrow Stromal Cells from Multi-Donors
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Mechanical Properties of Living Cells: Interaction of the Adherent Endothelial Cell and the Fluid Shear Flow
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Preliminary Study for Evaluating Bone Forming Ability of Porous Bioceramics Using Rat Mesenchymal Stem Cells to be Used for International Standard
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Reconstruction of Liver Organoid Using an Apatite-Fiber Scaffold, a Radial-Flow Bioreactor and FCL-4 Cells of Hepatocyte Model
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Behavior of Cellularized-Hydroxyapatite Implants Coated with Cyclo-DfKRG Peptides in Spongious Bone: Quantitative Comparison of Micro-Tomodensitometry and Histomorphometry
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Expression of ODF and ICAM-1 of Bone Marrow Mesenchymal Stem Cells is Enhanced with Osteogenic Differentiation
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HomeKey Engineering MaterialsKey Engineering Materials Vols. 361-363Mechanical Properties of Living Cells: Interaction...

Mechanical Properties of Living Cells: Interaction of the Adherent Endothelial Cell and the Fluid Shear Flow

Abstract:

In present study a theoretical model was established to simulate the interaction between the adherent endothelial cell and fluid shear flow. A two-dimensional computational fluid dynamics (CFD) was conducted to solve the model equations. The results showed that the model cell was deformed under steady shear flow. It spread along the flow direction, and decreased its height. The deformation index (DI) increased with Reynolds number of applied fluid flow. The DI of the cell increased greatly when the initial contact angle (α) was smaller than 130°, and then it was less important with the increase of α. These results suggest that the fluid shear flow may play a particular role in the mechanism of cell activation and in the regulation of endothelial cells functions.

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Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

1157-1160

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.1157

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Online since:

November 2007

Authors:

Xiao Heng Liu, Hong Mei Yin, Yi Lai, Long Juan Xue

Keywords:

Aderent Cell, Deformation Index, Fluid Shear Flow, Mechanical Property

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References

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