Fabrication of Encapsulated Ag Microsphere with Hydroxyapatite for Sustained-Release

Abstract:

Apatite nuclei were synthesized by raising pH of simulated body fluid (SBF). The apatite nuclei were attached to surfaces of Ag microspheres. Hydroxyapatite (HAp) was induced from the apatite nuclei and spread over whole surface area of the Ag microspheres in SBF, then encapsulated Ag microspheres with HAp were fabricated. The encapsulated Ag microspheres with HAp were soaked in saline and changes in Ag ion concentration in saline were measured. The encapsulated Ag microspheres with HAp showed sustained-release of Ag ion.

• Periodical: Key Engineering Materials (Volumes 361-363)
• Pages: 1199-1202
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.361-363.1199
• Online since: November 2007
• Authors: Takeshi Yabutsuka, Shinichiro Tsuboi, Mitsuhiro Hibino, Takeshi Yao
• Keywords: Ag, Apatite Nuclei, Biomimetic Method, Hydroxyapatite (HAP), Microcapsule, Simulated Body Fluid (SBF)

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