Growth Behavior of Rat Bone Marrow Cells on RF Magnetron Sputtered Bioglass- and Calcium Phosphate Coatings
The RF magnetron sputter technique was used to deposit Bioglass (BG) and hydroxyapatite (HA) coatings onto titanium substrates. The aim of this study was evaluated the growth behavior of rat bone marrow cells of various deposited coatings. The EDS measurements demonstrated that the composition BG coating was changed during magnetron sputtering. The rat bone marrow derived osteoblast-like cells showed improved osteogenic response on crystalline magnetron sputtered HA coatings compared BG coatings. Scanning electron microscopical examination showed an extensive mineralization after 16 days of culture, while on the surface of the BG coating only a multilayer without mineralization could be observed.
Guy Daculsi and Pierre Layrolle
J. G.C. Wolke et al., "Growth Behavior of Rat Bone Marrow Cells on RF Magnetron Sputtered Bioglass- and Calcium Phosphate Coatings", Key Engineering Materials, Vols. 361-363, pp. 253-256, 2008