Physicochemical Reactivity after the In Vitro Assays of Synthetic and Natural Hydroxyapatite
Bioactive ceramics such as bioactive glasses, calcium carbonate and sintered hydroxyapatite are widely used in biomaterials field because of their high biocompatibility. In this study, natural hydroxyapatite (N-HA) and synthetic Hydroxyapatite (S-HA) were heat treated at 800°C and studied using “in vitro” experiments. Several physicochemical methods like: SRD, FTIR, SEM and ICP-OES were employed to evaluate the effects of the thermal treatment and to compare their behaviour after soaking in the Simulated Body Fluid SBF at different times. The formation of TCP has favours the formation of new phase. Obtained results show that the dissolution occurred more in N-HA than in S-HA and consequently the precipitation of new phosphate phase is more important in N-HA. This is due to the presence of Mg, Sr and Zn in N-HA with concentration higher to that in S-HA.
Marcelo Prado and Cecília Zavaglia
H. Oudadesse et al., "Physicochemical Reactivity after the In Vitro Assays of Synthetic and Natural Hydroxyapatite", Key Engineering Materials, Vols. 396-398, pp. 261-264, 2009