New Injectable Bone Substitute Using Reversible Thermosensitive Hydrogel and BCP Granules: In Vivo Rabbit Experiments

Guy Daculsi; P.A. Uzel; N. Bourgeois; T. Le François; Jean Louis Rouvillain; Xavier Bourges; Serge Baroth

doi:10.4028/www.scientific.net/KEM.396-398.457

Paper Titles

Hydroxyapatite-Sheet Microstructure of Shinbone
p.441

Improvement of Bioactivity of Collagen/Alginate Scaffolds by Hydroxyapatite for Tissue Engineering Cartilage
p.445

In Vitro Osteoclast Differentiation of Bone Marrow Cells on Hydroxyapatite/Collagen Self-Organized Bone-Like Nanocomposite Disk
p.449

Investigation on Screwy Microstructure of Solid-Trough Shell
p.453

New Injectable Bone Substitute Using Reversible Thermosensitive Hydrogel and BCP Granules: In Vivo Rabbit Experiments
p.457

PLGA-Hydroxyapatite Composite Scaffolds for Osteoblastic-Like Cells
p.461

Preparation and Characterization of Fe₃O₄/Poly (2-Hydroxyethyl Methacrylate) Magnetic Nanocomposite Films
p.465

Rapidly Resorbable, Temporarily Mechanically Stable Composites for Bone Replacement
p.469

Resorbable Mesh Based on Calcium Alginate for Bone Reconstruction Surgical Technologies
p.473

HomeKey Engineering MaterialsKey Engineering Materials Vols. 396-398New Injectable Bone Substitute Using Reversible...

New Injectable Bone Substitute Using Reversible Thermosensitive Hydrogel and BCP Granules: In Vivo Rabbit Experiments

Abstract:

We have developed a new injectable bone substitute combining specific granules of BCP with or without radiopaque elements with a reversible thermo sensitive resorbable carrier such as Pluronic F-127. The composite is liquid at ambient temperature and set as hydrogel at 37°C. Rabbit experiment demonstrates high biocompatibility and bone ingrowth at the expense of the injectable bioceramic composite.