Assessing In Vitro Degradation of β-Tricalcium Phosphate Ceramics via Micro-Computed Tomography

A.B. Diggs; C.J. Bae; Wei Ju Tseng; C.L. Flanagan; J.W. Halloran; S.J. Hollister

doi:10.4028/www.scientific.net/KEM.396-398.637

Paper Titles

Synthesis and Characterization of Nanostructured Ceramic Powders of Calcium Phosphate and Hydroxyapatite for Dental Applications
p.619

Synthesis of Nanostructured Hydroxyapatite: A Comparative Study between Sol-Gel and Aqueous Solution Precipitation
p.623

Three-Layer Coating for Stents with Nanostructured Surface
p.627

A Novel Bone Scaffolds Based on Hyperbranched Polyglycerol Fibers Filled with Hydroxyapatite Nanoparticles: In Vitro Cell Response
p.633

Assessing In Vitro Degradation of β-Tricalcium Phosphate Ceramics via Micro-Computed Tomography
p.637

Bioactive Ceramics Based on Nb₂O₅ and Ta₂O₅
p.641

Calcium Phosphate Porous Materials with Unique Microstructures
p.645

Comparison of Hydroxyapatite and AB-Type Carbonate-Substituted Hydroxyapatite Suspensions for Use in the Reticulated Foam Method of Scaffold Production
p.649

Development of Calcium Phosphate Mineralized Silk for Potential Use in Guided Bone Regeneration: Preparation and Properties
p.653

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Assessing In Vitro Degradation of β-Tricalcium Phosphate Ceramics via Micro-Computed Tomography

Abstract:

This paper describes the use of micro-computed tomography for determining in vitro degradation of calcium-phosphate ceramic materials. Samples were immersed in a simulated body fluid and scanned at the initial and final timepoints. Analysis indicates degradation of material density as well as changes in mineral content and mineral density. Findings are confirmed with known methods of materials characterization (SEM, mass analysis, and Archimedes’s density calculations), indicating changes in surface morphology, mass, and pore volume.