Macroporous Calcium Phosphate Bioceramics as Drug Release Agents: A Kinetics Study of Ampicillin Release

Abstract:

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Semi-synthetic beta-lactam antibiotics are the most important class of antibacterial agents. Their use in veterinary and human medicine is in continuous expansion. Calcium phosphate bioceramics have been used in medicine and dentistry for nearly 30 years. Calcium phosphate ceramics (CPC) are nowadays being widely used as drug delivery systems because of their desirable properties such as biocompatibility, bioresorbability, controlled release etc. In recent years In this work, kinetic models to describe ampicillin adsorption from CPC were investigated. Calcium phosphate bioceramic are analogous to the mineral component of bones, its properties make it suitable for implant materials and delivery agents of drugs

Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Main Theme:

Edited by:

Marcelo Prado and Cecília Zavaglia

Pages:

675-678

DOI:

10.4028/www.scientific.net/KEM.396-398.675

Citation:

J.S.V. Albuquerque et al., "Macroporous Calcium Phosphate Bioceramics as Drug Release Agents: A Kinetics Study of Ampicillin Release", Key Engineering Materials, Vols. 396-398, pp. 675-678, 2009

Online since:

October 2008

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$35.00

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