Manufacturing of Porous Alumina Scaffolds with Bio-Glass and HAp Coating: Mechanical and In Vitro Evaluation
The objective of this study was to manufacture porous scaffolds with bioinert and bioactive materials to join mechanical properties and bony integration. Porous alumina ceramic matrices were produced using the slurry technique followed by isostatic pressing, leaching and sintering. Porous alumina samples presented 75.0vol% porosity and 52.27MPa of compressive strength. Bioglass/hydroxyapatite ceramic slurry was used as coating on alumina matrices. The infiltration was performed by dipping the alumina porous samples into bio-glass/hydroxyapatite ceramics slurry under vacuum and followed by sintering. The evaluation of the alumina ceramic scaffolds samples were made using EDX, mechanical and in vitro tests. For the in vitro tests, fibroblastic VERO cell line was employed. The porous alumina ceramic coated acquired a higher strength and more pronounced cell interaction than the non coated alumina scaffolds.
Marcelo Prado and Cecília Zavaglia
C. C. Camilo et al., "Manufacturing of Porous Alumina Scaffolds with Bio-Glass and HAp Coating: Mechanical and In Vitro Evaluation", Key Engineering Materials, Vols. 396-398, pp. 679-682, 2009