In Vitro Dynamic Degradation of Strontium-Hydroxyapatite Granules

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Abstract:

The knowledge of the degradation process is an important role to understand and predict in vitro results. Granules of strontium-hydroxyapatite (Sr-HA) were submitted to a degradation process under dynamic conditions using a bioreactor system and using a solution with pH=5. The degradation process under dynamic conditions can be represented by a curve in which the calcium content firstly increases (dissolution part) followed by calcium decreasing (reprecipitation). The use of a low pH solution does not affect the curve’s shape but reduces the precipitation step.

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Key Engineering Materials (Volumes 493-494)

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205-208

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October 2011

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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