Effect of Silver Concentration on Bioactivity and Antibacterial Properties of SiO2-CaO-P2O5 Sol-Gel Derived Bioactive Glass

Abstract:

Article Preview

Human beings are often infected by microorganisms in the living environment. Among various natural and inorganic substances, silver or silver ions have a powerful antibacterial activity. In the present study, the bioactivity and antibacterial activity of the SiO2–CaO–P2O5–Ag2O was compared with that of its ternary counterpart glass system (as a control sample) in vitro. The molar ratio of silver oxide in the bioactive glass composition was considered as different amount (0.5%, 1% and 2%). The surface characterization was evaluated after soaking in simulated body fluid (SBF). The sharpest apatite peak in X-ray diffraction (XRD) analyse after 7 days soaking in SBF was observed for 2% Ag sample (2%Ag-BG). Hence, the antibacterial effects of 2%Ag-BG sample against 2 gram negatives bacterium were examined by agar plate test. The result showed that the amount of silver did not prevent the HAp formation. Also, the antibacterial properties of 2%Ag-BG sample indicated near 100% bactericidal ratio (according to the width of antibacterial halo).

Info:

Periodical:

Key Engineering Materials (Volumes 493-494)

Main Theme:

Edited by:

Eyup Sabri Kayali, Gultekin Goller and Ipek Akin

Pages:

74-79

DOI:

10.4028/www.scientific.net/KEM.493-494.74

Citation:

N. Nezafati et al., "Effect of Silver Concentration on Bioactivity and Antibacterial Properties of SiO2-CaO-P2O5 Sol-Gel Derived Bioactive Glass", Key Engineering Materials, Vols. 493-494, pp. 74-79, 2012

Online since:

October 2011

Export:

Price:

$35.00

In order to see related information, you need to Login.

In order to see related information, you need to Login.