Recognition and Electrochemical Sensing of 8-Hydroxydeoxyguanosine with Molecularly Imprinted Poly (ethylene-co-vinyl alcohol) Thin Films
Biosensors using the mechanisms of electrochemical, optical, mass sensitive thermometric and magnetometric have been intensively investigated , and molecularly imprinted polymers (MIPs) has been used as recognition elements in sensors reviewed in numerous articles [1-3]. A severe challenge for MIP sensors is detection in chemically diverse environments, such as biological fluids [4-7]. There are many biomarkers discovered in biological fluid, like cerebrospinal fluid (CSF), saliva, serum and urine. Important biomarkers such as creatinine , urea, and albumin , urine contains non-protein nitrogen metabolites, carbohydrates , proteins and amino acids ; detection of analytes must be made amid this complex chemical background.
E. Hristoforou and D.S. Vlachos
M. H. Lee et al., "Recognition and Electrochemical Sensing of 8-Hydroxydeoxyguanosine with Molecularly Imprinted Poly (ethylene-co-vinyl alcohol) Thin Films", Key Engineering Materials, Vol. 495, pp. 331-334, 2012