Titanium and Ti-13Nb-13Zr Alloy Porous Implants Obtained by Space-Holder Technique with Addition of Albumin

Abstract:

Titanium and its alloys are the main metals studied as porous metallic implants by their excellent mechanical properties and biological interactions. Production methods of porous metallic materials are based on powder metallurgy (PM), because it allows the manufacturing of parts with complex shapes and dimensions close to the finals (near-net shape), and the addition of alloying elements reaching a satisfactory structural homogeneity, and porosity. The pore production by space-holder technique constitutes of mixing organic compounds with metal powder, which when removed by thermal treatment prior structures are kept in place. The objective of this study is to obtain porous implants of commercially pure titanium (cpTi) and Ti-13Nb-13Zr alloy by PM with space-holder technique and albumin as an additive. For the processing of the samples were used hydride titanium powder (TiH₂) to obtain cpTi samples, and metal powders of Ti, Nb and Zr in the stoichiometric proportions for obtaining the alloy samples. The samples were prepared by mixing the metallic powder to the albumin (30wt%) and filling a silicone model that was pressed isostatically (140 MPa). The thermal treatment was performed in an oxidizing atmosphere (350°C/1h) for the decomposition of organic material. The sintering was performed at a temperature of 1300°C (1h/cpTi, 3h/Alloy) in high vacuum furnace (10^-5 mBar) to all samples. The calculated porosity showed a significant difference between the samples cpTi (40%) and alloy (60%). The samples surface characterization showed very rough with high specific surface area. Samples of cpTi presented formation of necks arising from sintering. In the alloy samples were observed homogenous microstructure with the presence of α and β phases composing the Widmanstätten structure. It is possible to conclude that the same amount albumin allowed the formation of pores in the microstructure of cpTi and alloy although in different proportions, without harming the sintering of both and allowing diffusion of the alloy elements.

• Periodical: Key Engineering Materials (Volumes 529-530)
• Pages: 574-579
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.529-530.574
• Online since: November 2012
• Authors: Tamiye Simone Goia, Kalan Bastos Violin, José Carlos Bressiani, Ana Helena de Almeida Bressiani
• Keywords: Albumin, Porosity, Titanium

References

[1] J.P. St-Pierre, M. Gauthier, L.P. Lefebvre, M. Tabrizian, Three-dimensional growth of differentiating MC3T3-E1 pre-osteoblasts on porous titanium scaffolds. Biomat. 26(2005)7319-28.

DOI: 10.1016/j.biomaterials.2005.05.046

[2] G. Ryan, A. Pandit, D.P. Apatsidis, Fabrication methods of porous metals for use in orthopaedic applications, Biomat. 27(2006) 2651-70.

DOI: 10.1016/j.biomaterials.2005.12.002

[3] J.P. Li, S.H. Li, C.A.V. Blitterswijk, K. Groot, A novel porous Ti6Al4V: characterization and cell attachment, J. Biomed. Mat. Res. 73A (2005) 223-233.

DOI: 10.1002/jbm.a.30278

[4] A. Laptev, M. Bram, H.P. Buchkkemer, D. Stover, Study of production route for titanium parts combining very high porosity and complex shape, Powder Metal. 47 (2004) 85-92.

DOI: 10.1179/003258904225015536

[5] A.E. Aguikar Maya, D.R. Grana, A. Hazarabedian, G.A. Kokubo, M.I. Luppo, G. Vigna, Zr-Ti-Nb porous alloy for biomedical application, Mat. Sci. Eng. C. 32 (2011) 321-329.

DOI: 10.1016/j.msec.2011.10.035

[6] Y.J. Chen, B. Feng, Y.P. Zhu, J. Weng, J.X. Wang, X. Lu, Fabrication of porous titanium implants with biomechanical compatibility, Mat. Letters 63 (2009) 2659–2661.

DOI: 10.1016/j.matlet.2009.09.029

[7] D.K. Pattanayak, T. Matsushita, K. Doi, H. Takadama, T. Nakamura, T. Kokubo, Effects of oxygen content of porous titanium metal on its apatite-forming ability and compressive strength. Mat. Sci. Eng: C, 29 (2009) 1974-(1978).

DOI: 10.1016/j.msec.2009.03.014

[8] L.M. Vasconcellos, D.O. Leite, F.O. Nascimento, L.G. Vasconcellos, M.L. Graça, Y.R. Carvalho; C.A. Cairo, Porous titanium for biomedical applications: An experimental study on rabbits. Med Oral Patol Oral Cir Bucal, 15 (2010) 407-412.

DOI: 10.4317/medoral.15.e407

[9] C. Ribeiro, T.S. Goia, K.B. Violin, J.C. Bressiani, A.H.A. Bressiani, Osseointegration and biocompatibility study of macroporous biphasic calcium phosphate (BCP) ceramics obtained by consolidation using albumin. Adv. Sci. Tech. Vol. 76, pp.66-71, (2010).

DOI: 10.4028/www.scientific.net/ast.76.66

[10] ASTM C20-00. Standard test methods for apparent porosity, water absorption, apparent specific gravity, and bulk density of burned refractory brick and shapes by boiling water.

DOI: 10.1520/c0020-97