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HomeKey Engineering MaterialsKey Engineering Materials Vol. 587Influence of Nanograin Size ZrO2 and Al2O3...

Influence of Nanograin Size ZrO₂ and Al₂O₃ Ceramics on Biological Response of Cells

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Abstract:

The influence of the grain size of alumina and zirconia ceramics on the spreading and adhesion of MG63 cell lines was investigated. Single-component ceramics and layered composite ceramics were prepared by electrophoretic deposition, uniaxial pressing and sintering. The grain size of zirconia was 100 nm to 2.7 μm and that of alumina was 0.5 μm to 1.5 μm. Subsequently, sample surfaces were polished and thermally etched. Biological tests of adhesion (0.5 to 8 h) were used to evaluate the influence of grain size on biological response. The highest cell spreading was obtained for ZrO₂ ceramics with an average grain size of 100 and 120 nm. The cell selection was observed on layered ZrO₂/Al₂O₃ composites. The cells predominantly adhered to ZrO₂ layers. The results showed a positive influence of nanostructured ceramic surfaces on biological behaviour of MG63 cells.

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Bioceramics 25

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Periodical:

Key Engineering Materials (Volume 587)

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132-137

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https://doi.org/10.4028/www.scientific.net/KEM.587.132

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Online since:

November 2013

Authors:

Aleš Matoušek*, Martina Kukletová, Jaroslav Cihlář

Keywords:

Alumina, Bioactivity, Cell Adhesion, Micro/Nanometric Grains, Osteoblast Cell, Surface Roughness (SR), Zirconia

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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