Nanoparticles for Biomedical Applications Prepared by CO2 Laser Vaporization

Frank A. Müller; Heinz Dieter Kurland; Janet Grabow

doi:10.4028/www.scientific.net/KEM.587.154

Paper Titles

Production and Characterization of Hydroxyapatite/Niobo Phosphate Glass Scaffold
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Influence of Nanograin Size ZrO₂ and Al₂O₃ Ceramics on Biological Response of Cells
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Novel Bioactive Materials neither Based on Calcium Phosphate Nor Silicate: Titanium Oxide
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Production and Mechanical Properties of Commercial Synthetic Hydroxyapatite (CSHA) Composites
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Nanoparticles for Biomedical Applications Prepared by CO₂ Laser Vaporization
p.154

Fabrication of Magnetic Hydroxyapatite Microcapsule for Protein Collection
p.160

Fabrication of Bioactive Apatite Nuclei Precipitated Polylactic Acid by Using Sandblasting Process
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Exploring Zinc Apatites through Different Synthesis Routes
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Biodegradability of some Collagen Sponges Reinforced with Different Bioceramics
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HomeKey Engineering MaterialsKey Engineering Materials Vol. 587Nanoparticles for Biomedical Applications Prepared...

Nanoparticles for Biomedical Applications Prepared by CO₂ Laser Vaporization

Abstract:

Functional ceramic nanopowders with emphasis on biomedical applications were engineered by gas-phase condensation using the CO₂ laser vaporization (LAVA) technique. Europium doped strontium aluminate nanoparticles (NP) were prepared from a SrO/α-Al₂O₃/Eu₂O₃ powder mixture. Excited with ultraviolet radiation (UV), the as-prepared amorphous NP revealed red photoluminescence emission. After annealing in reductive atmosphere crystalline SrAl₂O₄:Eu²⁺ nanopowder was obtained showing strong green emission at UV excitation. Ferrimagnetic iron oxide (Fe_xO_y) nanopowders were prepared starting from α-Fe₂O₃ powder. In oxygen-free condensation atmosphere γ-Fe₂O₃ NP were obtained. Oxygen as condensation gas yielded γ-and ε-Fe₂O₃ NP. Superparamagnetic NP were prepared starting from α-Fe₂O₃/SiO₂ mixtures. Depending on the mixing ratio γ-Fe₂O₃ nanocrystallites embedded in a SiO₂ glass matrix or γ-Fe₂O₃-SiO₂ Janus NP were obtained. These NP provide a reactive SiO₂ interface for subsequent functionalizing. The co-vaporization of α-Al₂O₃ as the main proportion and t-ZrO₂ yielded zirconia-toughened-alumina NP. Reinforcing effects of Al₂O₃-ZrO₂ dispersion ceramics will be increased using NP with an intraparticle dispersion of these phases. Future applications of the LAVA prepared NP include biological fluorescence labeling, and drug targeting, magnetic resonance imaging, and hyperthermic cancer therapy, as well as sintering of load bearing ceramic implants, respectively.

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Periodical:

Key Engineering Materials (Volume 587)

Pages:

154-159

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.587.154

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Online since:

November 2013

Authors:

Frank A. Müller, Heinz Dieter Kurland, Janet Grabow

Keywords:

Al₂O₃-ZrO₂, Dispersion Ceramic, Fe₂O₃-SiO₂, Janus Nanoparticles, Laser Vaporisation, Nanoparticle, Photoluminescence (PL), SrAl₂O₄:Eu, Superparamagnetism, γ-Fe₂O₃, ε-Fe₂O₃

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