Fabrication of Magnetic Hydroxyapatite Microcapsule for Protein Collection

Shun Kumazawa; Daiki Hisashuku; Takeshi Yabutsuka; Takeshi Yao

doi:10.4028/www.scientific.net/KEM.587.160

Paper Titles

Influence of Nanograin Size ZrO₂ and Al₂O₃ Ceramics on Biological Response of Cells
p.132

Novel Bioactive Materials neither Based on Calcium Phosphate Nor Silicate: Titanium Oxide
p.141

Production and Mechanical Properties of Commercial Synthetic Hydroxyapatite (CSHA) Composites
p.147

Nanoparticles for Biomedical Applications Prepared by CO₂ Laser Vaporization
p.154

Fabrication of Magnetic Hydroxyapatite Microcapsule for Protein Collection
p.160

Fabrication of Bioactive Apatite Nuclei Precipitated Polylactic Acid by Using Sandblasting Process
p.165

Exploring Zinc Apatites through Different Synthesis Routes
p.171

Biodegradability of some Collagen Sponges Reinforced with Different Bioceramics
p.179

Fish Scales as a Biocomposite of Collagen and Calcium Salts
p.185

HomeKey Engineering MaterialsKey Engineering Materials Vol. 587Fabrication of Magnetic Hydroxyapatite...

Fabrication of Magnetic Hydroxyapatite Microcapsule for Protein Collection

Abstract:

When pH or temperature of simulated body fluid (SBF) is raised, fine particles of calcium phosphate are precipitated. We found that this fine particle actively induces hydroxyapatite from body fluid or SBF and named the particle Apatite Nucleus (AN). In this study, we attached AN on the surface of γ-Fe₂O₃ nanoparticles and soaked them in SBF. By this treatment, hydroxyapatite was induced from AN and covered the whole surface of the γ-Fe₂O₃ nanoparticles, then hydroxyapatite microcapsule encapsulated γ-Fe₂O₃ was fabricated. We dispersed the microcapsules in urease solution, and collected the microcapsules by neodymium magnet. It was indicated that the urease was adsorbed to the hydroxyapatite microcapsules and collected by the magnetism of γ-Fe₂O₃successfully.

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Periodical:

Key Engineering Materials (Volume 587)

Pages:

160-164

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.587.160

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Online since:

November 2013

Authors:

Shun Kumazawa, Daiki Hisashuku, Takeshi Yabutsuka, Takeshi Yao

Keywords:

Apatite Nucleus (AN), Magnetic Hydroxyapatite Microcapsule (MHM), Protein Collection, Simulated Body Fluid (SBF), γ-Fe₂O₃

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